You can use these hooks for many different flies. I use them to make CDC emergers because of the fine wire they are made out of. I also use them to make midge pupa because of the small sizes available.
The down eye on this hook makes it easier for thread to jump off the front of the hook. Especially for beginners. The 2488 has a straight eye making it easier to avoid that problem. Just be careful not to crowd the eye. (Beginner mistake)